Do people with Down syndrome have Epicanthic folds?

An epicanthal fold is a skin fold of the upper eyelid covering the inner corner of the eye. It is often seen as a normal finding in very young children and is also common in people of Asiatic decent. An epicanthal fold can be an important diagnostic finding in conditions such as Down syndrome.

Is single palmar crease hereditary?

Males are twice as likely as females to have this characteristic, and it tends to run in families. In its non-symptomatic form, it is more common among Asians and Native Americans than among other populations, and in some families there is a tendency to inherit the condition unilaterally; that is, on one hand only.

Does simian crease mean Down syndrome?

A single palmar crease occurs in about 1 out of 30 people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.

Can Epicanthal folds be normal?

Epicanthal folds may be normal for people of Asiatic descent and some non-Asian infants. Epicanthal folds also may be seen in young children of any race before the bridge of the nose begins to rise. However, they may also be due to certain medical conditions, including: Down syndrome.

How is the epicanthal fold related to Down’s syndrome?

Someone with Down’s syndrome is trisomy at 21 i.e., the presence of chromosome 21 in three copies. It is an autosomal disorder and is characterised by the eyes that slant upwards and have an extra skin fold on the upper eyelid known as an epicanthal fold.

How often do palmar creases occur in the palm?

There are typically two creases in the palm, but in some people, only one crease is present. A single palmar crease occurs in about 1 out of 30 people, but is also frequently associated with other conditions such as Down syndrome, Aarskog syndrome or fetal alcohol syndrome.

Is the epicanthal skin fold an autosomal disorder?

It is an autosomal disorder and is characterised by the eyes that slant upwards and have an extra skin fold on the upper eyelid known as an epicanthal fold. This skin fold covers the inner corner of their eye next to their nose. The single palmar crease is a single, deep, crease across the palm of the hand previously referred to as simian crease.

Where is the skin fold on the epicanthal hand?

This skin fold covers the inner corner of their eye next to their nose. The single palmar crease is a single, deep, crease across the palm of the hand previously referred to as simian crease. Was this answer helpful?