How do you infuse LEVOPHED?

Average Dosage: Add a 4 mL ampul (4 mg) of LEVOPHED to 1,000 mL of a 5 percent dextrose containing solution. Each mL of this dilution contains 4 mcg of the base of LEVOPHED. Give this solution by intravenous infusion.

Can LEVOPHED be given io?

Administration through IO in the leg is permitted. : In the setting of tachydysrhythmia-induced cardiogenic shock, treat per Unstable Tachycardia protocol.

How do you infuse Norepinephrine?

Noradrenaline (Norepinephrine) should only be administered as an intravenous infusion via a central venous catheter to minimize the risk of extravasation and subsequent tissue necrosis. Noradrenaline (Norepinephrine) should be infused at a controlled rate using an infusion pump.

Can Norepinephrine be given IV?

LEVOPHED is supplied in sterile aqueous solution in the form of the bitartrate salt to be administered by intravenous infusion following dilution. Norepinephrine is sparingly soluble in water, very slightly soluble in alcohol and ether, and readily soluble in acids.

What should I start with Levophed?

The physician orders a Levophed drip to be started at 0.5 mcg/min with parameters ordered to keep SBP>90 and heart rate less than 120. After 20 min, the patient vital signs are heart rate of 106, B/P 88/42, Saturation 96%.

What Cannot be given through an IO?

Contraindications to IO insertion include fracture at or proximal to the insertion site, cellulitis or other infection overlying the insertion site, prior attempt at the insertion site, or bone disease such as osteogenesis imperfecta or osteopetrosis.

What feelings does norepinephrine produce?

Bursts of norepinephrine can lead to euphoria (very happy) feelings but are also linked to panic attacks, elevated blood pressure, and hyperactivity. Low levels can cause lethargy (lack of energy), lack of concentration, attention deficit hyperactivity disorder (ADHD), and possibly depression.

What is another name for norepinephrine?

Norepinephrine is available under the following different brand names: Levarterenol, and Levophed.

When to use levophed before or after blood volume replacement?

When, as an emergency measure, intraaortic pressures must be maintained to prevent cerebral or coronary artery ischemia, Levophed can be administered before and concurrently with blood volume replacement. Diluent: Levophed should be diluted in 5 percent dextrose injection or 5 percent dextrose and sodium chloride injections.

Why do I need to avoid extravasation of levophed?

to avoid extravasation of LEVOPHED into the tissues, as local necrosis might ensue due to the vasoconstrictive action of the drug. Blanching along the course of the infused vein, sometimes without obvious extravasation, has been attributed to vasa vasorum constriction with increased permeability of the vein wall, permitting some leakage.

Is it safe to use levophed during cyclopropane anesthesia?

Hence, the use of LEVOPHED during cyclopropane and halothane anesthesia is generally considered contraindicated because of the risk of producing ventricular tachycardia or fibrillation. The same type of cardiac arrhythmias may result from the use of LEVOPHED in patients with profound hypoxia or hypercarbia.

How much levophed should I take for refractory shock?

Individual response is highly variable. Patients with refractory shock may require dosages of 8 to 30 mcg/minute. There are rare situations in which much larger doses (as high as 68 mg/day or 47 mcg/minute) may be necessary if the patient remains hypotensive; however, rule out hidden blood volume depletion.