What is Supprelin LA used for?

Histrelin implant (Supprelin LA) is used to treat central precocious puberty (CPP; a condition causing children to enter puberty too soon, resulting in faster than normal bone growth and development of sexual characteristics) in girls usually between 2 and 8 years of age and in boys usually between 2 and 9 years of age …

How big is supprelin implant?

Hypothetical patient. The implant is a small, thin, flexible tube measuring 3.5 cm by 3 mm. Not actual size. The SUPPRELIN® LA implant is packaged hydrated in a 3.5-mL glass vial containing 2 mL of sterile 1.8% sodium chloride solution, so that it is primed for immediate release of the drug upon insertion.

Does supprelin cause weight gain?

Weight gain It’s possible for children to gain weight while they’re using Supprelin LA. Clinical studies showed that 2% of children had weight gain during treatment.

Does supprelin stop growth?

This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment. Histrelin is also used by children to treat early puberty (central precocious puberty).

Does milk cause early puberty?

Fact: There is no scientific evidence that drinking milk causes early puberty. In the United States, girls are entering puberty at younger ages than they were in the first half of the 20th century. Researchers do not know the exact trigger for early-onset puberty, although it is likely influenced by many factors.

What hormone causes precocious puberty?

Estrogen or testosterone in your child’s body causes this type of precocious puberty.

How much does a histrelin implant cost?

The average wholesale price of the histrelin implant is US$16,800. 11 The cost related to placement and removal of the histrelin implant is not included in this price.

Is supprelin a hormone?

SUPPRELIN LA is an under-the-skin (subcutaneous) implant that contains the medicine histrelin, a gonadotropin releasing hormone (GnRH). SUPPRELIN LA is used for treatment of children with central precocious puberty (CPP).

How is supprelin implanted?

SUPPRELIN LA is placed under the skin of the inside of the upper arm. The doctor will temporarily numb the arm of your child, make a small cut, and then place SUPPRELIN LA under the skin. The cut may be closed with stitches or surgical strips and covered with a pressure bandage.

How does histrelin treat precocious puberty?

Histrelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily. The Supprelin LA brand of histrelin is used to treat precocious puberty in both male and female children who are at least 2 years old.

What foods help puberty?

Protein-rich foods include lean meat, fish, chicken, eggs, beans, lentils, chickpeas, tofu and nuts. These foods are important for your child’s growth and muscle development, especially during puberty.

What is supprelin implant made of?

SUPPRELIN LA is designed to deliver approximately 65 mcg histrelin acetate per day over 12 months. The SUPPRELIN LA implant looks like a small thin flexible tube and consists of a 50-mg histrelin acetate drug core inside a 3.5 cm by 3 mm, cylindrical, hydrogel polymer reservoir (Figure 1).

Histrelin works by reducing the amount of testosterone that the body makes. This helps slow or stop the growth of cancer cells and helps relieve symptoms such as painful/difficult urination. Talk to your doctor about the risks and benefits of treatment.

Is supprelin implant covered by insurance?

The cost for Supprelin LA subcutaneous implant 50 mg is around $44,973 for a supply of 1 implant, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. Supprelin LA is available as a brand name drug only, a generic version is not yet available.

What causes precocious puberty?

The less common peripheral precocious puberty occurs without the involvement of the hormone in your brain (GnRH) that normally triggers the start of puberty. Instead, the cause is release of estrogen or testosterone into the body because of problems with the ovaries, testicles, adrenal glands or pituitary gland.

Is precocious puberty genetic?

The most common known genetic cause of central precocious puberty is mutations in the MKRN3 gene. Changes in other genes are rare causes of the condition, and researchers suspect that changes in genes that have not yet been identified may also be involved in central precocious puberty.

How long does supprelin last?

The 50 mg histrelin implant provides continuous release of the potent gonadotropin releasing hormone analog (GnRHa) histrelin for the treatment of central precocious puberty (CPP). Because histrelin is released at ~65 mcg per day,2 a single implant of a “yearly” device theo-retically would last 2 years.

Is vantas the same as supprelin?

The main difference between the two medicines is that Supprelin LA releases 65 micrograms of the drug a day and Vantas releases 50 micrograms a day. Each implant lasts about a year.

Are puberty blockers expensive?

The cost of puberty blockers is approximately $1,200 per month for injections and can range from $4,500 to $18,000 for an implant. The least expensive form of estrogen, a pill, can cost anywhere between $4 to $30 a month, according to Simons, while testosterone can be anywhere between $20 to $200 a vial.

What food causes early puberty?

Higher total protein, animal protein and meat intake in children ages 3 to 7 have been associated with earlier onset of menstruation. High protein intake elevates IGF-1 levels and promotes growth, which could accelerate the onset of puberty. Poor diet. Children with lower-nutrient diets tend to enter puberty earlier.

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What do you need to know about Supprelin LA?

Supprelin LA (histrelin) is a man-made form of a hormone that regulates many processes in the body. Histrelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily. Supprelin LA implants are used to treat precocious puberty in both male…

How old do you have to be to take Supprelin LA?

SUPPRELIN® LA is an implanted gonadotropin releasing hormone (GnRH) medicine used for the treatment of children with central precocious puberty (CPP). It is not known if SUPPRELIN® LA is safe and effective in children under 2 years of age.

What are the side effects of Supprelin LA implants?

Supprelin LA implants are used to treat precocious puberty in both male and female children who are at least 2 years old. Supprelin LA may also be used for purposes not listed in this medication guide. Supprelin LA can harm an unborn baby or cause a miscarriage.

When to use Supprelin LA for puberty treatment?

Histrelin overstimulates the body’s own production of certain hormones, which causes that production to shut down temporarily. Supprelin LA implants are used to treat precocious puberty in both male and female children who are at least 2 years old. Supprelin LA may also be used for purposes not listed in this medication guide.