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How does citalopram metabolized?

How does citalopram metabolized?

Citalopram is metabolized mainly in the liver via N-demethylation to its main metabolite, demethylcitalopram by CYP2C19 and CYP3A4 7. Other metabolites include didemethylcitalopram via CYP2D6 metabolism, and citalopram N-oxide via monoamine oxidase enzymes and aldehyde oxidase.

How fast is citalopram absorbed?

After oral administration, citalopram is rapidly absorbed, with peak plasma levels observed approximately after 1–4 h and a plasma half-life of approximately 35 h after administration [8–10].

How is citalopram synthesized?

Synthesis of citalopram is proposed to occur by two general routes, usually called the anion strategy and the double Grignard strategy (Scheme 7.12.). Scheme 7.12. Synthesis of citalopram and escitalopram. In both cases, synthesis is started from a reaction of phthalide (7.3.

Is citalopram 10 mg a narcotic?

To my knowledge, citalopram is not considered a narcotic. I have been on drug for several years now. It is a very good drugs for depression.

What is citalopram prescribed for?

Citalopram is a selective serotonin reuptake inhibitor found under the brand name Celexa. It is most often prescribed to treat depression. Less frequently, it is prescribed to treat eating disorders, panic disorder, premenstrual dysphoric disorder (PMDD), social phobia, and alcoholism. How Citalopram Works.

What is citalopram 20 mg?

Citalopram tablets contain the active ingredient citalopram 20mg, an antidepressant belonging to the class of drugs known as selective serotonin reuptake inhibitors ( SSRI ), used to treat major depression.

Is Celexa also used for fibromyalgia pain?

Celexa for Pain. According to the Mayo Clinic, antidepressants may be helpful in reducing fibromyalgia pain. It may also promote sleep and reduce fatigue. This medication works by increasing serotonin in the brain, which appears to minimize pain in patients.