What is the cost of GeneXpert?

Warranty

What sample is used for GeneXpert?

How it works ———— The Gene Xpert is a machine that can detect *mycobacterium tuberculosis* in a sample of sputum. A person suspected of having TB needs to give a sputum sample, which the health care worker than places in a small tube.

How is GeneXpert test done?

A sputum sample is collected from the patient with suspected TB. The sputum is mixed with the reagent that is provided with the assay, and a cartridge containing this mixture is placed in the GeneXpert machine. All processing from this point on is fully automated.

Why GeneXpert test is done?

Introduction: Gene-Xpert, a CBNAAT (catridge based nucleic acid amplification test) is a widely accepted diagnostic test for Tuberculosis. This test is a rapid diagnostic test for Tuberculosis detection as well as Rifampicin resistance in direct smear negative cases.

What is the principle of GeneXpert?

Principle of the Procedure The Xpert MTB/RIF Assay is an automated in vitro diagnostic test using nested real-time PCR for the qualitative detection of MTB-complex and RIF resistance. The primers in this test amplify a portion of the rpoB gene containing the 81 base pair core region.

How do you get samples for GeneXpert?

How sensitive is GeneXpert?

GeneXpert showed high sensitivity (84.3%), specificity (100%), with positive predictive value (100%), and negative predictive value (96.7%), while Zn smear showed sensitivity 18.3%, specificity 99.1%, positive predictive value 81.8%, and negative predictive value 85.4%.

How long is GeneXpert positive?

show that after the completion of appropriate treatment, GeneXpert can produce false-positive results for up to 4 years and in 8.72% of positive tests on respiratory samples for up to 18 months, possibly due to both the presence of residual mycobacterial DNA in the respiratory tract and the detection of non-viable …

What is the difference between GeneXpert and TB PCR?

For Smear positive specimens, Xpert MTB/RIF assay showed 93.8% sensitivity, which was higher than Advansure TB/NTM real-time PCR at 87.5%. On the other hand, for smear negative specimens, Xpert MTB/RIF assay showed 65.5% sensitivity, which was lower than Advansure TB/NTM real-time PCR at 75.9%.

What is the difference between a rapid test and a PCR test?

Rapid Antigen Tests This test involves collecting nose and throat secretions via nasopharyngeal swab and then examining them for protein fragments specific to the COVID-19 virus. While these tests provide quick results—within 15 minutes—they are generally considered to be less accurate than PCR tests.

How much does it cost for a GeneXpert cartridge?

But the ground breaker in the whole arrangement is the discovery by the Cepheid team, – that you can use that cartridge on any GeneXpert platform and you will be able to get a result in 45 minutes. The cost for a cartridge is $19.8 (N7,128). ‘In a day, 96 tests can be performed with a single four modular GeneXpert.

What kind of tests can you get with GeneXpert?

The public sector in eligible countries can purchase test cartridges for TB, SARS-CoV-2, hepatitis C, hepatitis B, HIV, Ebola virus, human papillomavirus (HPV), Chlamydia trachomatis (CT)/ Neisseria gonorrhoeae (NG), and Trichonoma vaginalis (TV) at the prices listed below, ex-works and prepaid.

How does accesscare work with GeneXpert-find?

AccessCare simplifies service budget management by combining the additional cost into cartridge pricing. Further details may be obtained from Cepheid. FIND has leveraged its investment in the development of Xpert MTB/RIF by negotiating a price reduction agreement with Cepheid.

Can a GeneXpert machine be used to diagnose SARS?

GeneXpert machine The GeneXpert machine is a ‘reference lab quality’ test that can be run at the point of care to rapidly detect SARS-CoV-2, the virus that causes COVID-19. Unlike when it is used to diagnose TB and HIV, for COVID-19 test, it uses a different kind of cartridge.