What IV fluids are compatible with meropenem?

What IV fluids are compatible with meropenem?

Compatibility: Solutions Compatible: D5W, 0.9%NS, D5NS, ringer’s solution, ringer’s lactate.

Are Merrem and dextrose compatible?

Solutions of MERREM I.V. (MERREM I.V. concentrations ranging from 1 to 20 mg/mL) in Water for Injection or Sodium Chloride Injection 0.9% (for up to 48 hours) or in Dextrose Injection 5% (for up to 6 hours) are stable at 4ºC (39ºF) in plastic syringes.

What is meropenem compatible with?

Findings: Of the 88 medications tested, meropenem/vaborbactam was compatible with 73 (83%), including many antibiotics such as aminoglycosides (amikacin, gentamicin, and tobramycin), colistin, fosfomycin, linezolid, tedizolid, tigecycline, and vancomycin.

Can you give meropenem IV?

Meropenem is usually given by intravenous infusion over approximately 15 to 30 minutes (see section 6.2, 6.3 and 6.6). Alternatively, doses up to 1 g can be given as an intravenous bolus injection over approximately 5 minutes.

What are the contraindications of meropenem?

Who should not take MEROPENEM?

  • diarrhea from an infection with Clostridium difficile bacteria.
  • decreased blood platelets.
  • lesion of the brain.
  • seizures.
  • chronic kidney disease stage 4 (severe)
  • chronic kidney disease stage 5 (failure)
  • kidney disease with likely reduction in kidney function.

Can meropenem be given with normal saline?

The mean meropenem concentrations reconstituted in normal saline solution decreased 1.66%, 3.31% and 5.80% after 2, 4 and 8 hours storage at 20 degrees C, respectively. Drug concentrations decreased 3.14%, 5.86% and 11.85% after 2, 4 and 8 hours storage at 32 degrees-37 degrees C, respectively.

What is Merrem IV used for?

Meropenem injection is used to treat infections caused by bacteria. It works by killing the bacteria or preventing their growth. This medicine will not work for colds, flu, or other virus infections. This medicine is to be given only by or under the direct supervision of your doctor.

How many days should meropenem be given?

Clinical practice guidelines recommend meropenem for 4 to 7 days for severe or high-risk community-acquired infections or complicated health-care associated infections. 20 mg/kg/dose IV every 8 hours (Max: 1 g/dose).

Is Zyvox and meropenem compatible?

Interactions between your drugs No interactions were found between meropenem and Zyvox. This does not necessarily mean no interactions exist.

Is Merrem and potassium compatible?

Meropenem is compatible with potassium chloride (KCl) in concentrations of IO mmol/L and 40 mmol/L in NS and D5W at 23°C.

What bacteria does meropenem treat?

Meropenem is indicated for the treatment of bacterial meningitis caused by Streptococcus pneumoniae, β-lactamase-producing and non-β-lactamase-producing isolates of Haemophilus influenzae, and Neisseria meningitidis in children aged ⩾3 months [12].

What is the side effects of meropenem?

What are the side effects of Meropenem (Merrem)?

  • severe stomach pain, diarrhea that is watery or bloody;
  • a seizure (convulsions);
  • sores or white patches in your mouth or throat (yeast infection or “thrush”);
  • severe tingling or numbness; or.

What should the room temperature be for Merrem IV?

MERREM IV is supplied in 20 mL and 30 mL injection vials containing sufficient meropenem to deliver 500 mg or 1 gram for intravenous administration, respectively. The dry powder should be stored at controlled room temperature 20°25°C (68°-77°F) [see USP].

How long does it take to give Merrem IV?

MERREM IV should be administered by intravenous infusion over approximately 15 minutes to 30 minutes. Doses of 1 gram may also be administered as an intravenous bolus injection (5 mL to 20 mL) over approximately 3 minutes to 5 minutes. Use In Adult Patients With Renal Impairment

Can you mix Merrem i.v.with other drugs?

Compatibility of MERREM I.V. with other drugs has not been established.MERREM I.V. should not be mixed with or physically added to solutions containing other drugs.

How long does Merrem i.v.stay stable?

Infusion vials of MERREM I.V. constituted with Dextrose Injection 5% (MERREM I.V. concentrations ranging from 2.5 to 50 mg/mL) are stable for up to 1 hour at controlled room temperature 15-25°C (59-77°F) or for up to 8 hours at 4°C (39°F).