Where can myelinated fibers be found?

The area of myelination clinically is most commonly found continuous with the optic disc, but it may be seen isolated in other parts of the neural retina.

What are myelinated fibers?

Myelinated retinal nerve fiber layers (MRNF) are retinal nerve fibers anterior to the lamina cribrosa that, unlike normal retinal nerve fibers, have a myelin sheath. Clinically, they appear to be gray-white well-demarcated patches with frayed borders on the anterior surface of the neurosensory retina.

Where is the myelin sheath located?

The myelin sheath is a greatly extended and modified plasma membrane wrapped around the nerve axon in a spiral fashion [1]. The myelin membranes originate from and are a part of the Schwann cells in the peripheral nervous system (PNS) and the oligodendroglial cells in the central nervous system (CNS) (see Chap. 1).

Where are the oligodendrocytes found?

central nervous system
Oligodendrocyte, a type of neuroglia found in the central nervous system of invertebrates and vertebrates that functions to produce myelin, an insulating sheath on the axons of nerve fibres.

What do oligodendrocytes produce?

Oligodendrocytes are the myelinating cells of the central nervous system (CNS). They are the end product of a cell lineage which has to undergo a complex and precisely timed program of proliferation, migration, differentiation, and myelination to finally produce the insulating sheath of axons.

What causes Neurilemma?

Neurolemma (also neurilemma and sheath of Schwann) is the outermost layer of nerve fibers in the peripheral nervous system. It is a nucleated cytoplasmic layer of schwann cells that surrounds the myelin sheath of axons.

What do you mean by myelinated nerve fiber layer?

Myelinated Nerve Fiber Layer. Darin R. Goldman, in Atlas of Retinal OCT: Optical Coherence Tomography, 2018. Myelinated nerve fiber layer (mNFL) is a benign clinical entity that results from an embryologic developmental anomaly whereby focal areas of the retinal nerve fiber layer fail to lose their myelin sheath.

How big is the myelin sheet of the sciatic nerve?

The myelin sheet of myelinated nerve fiber was varied in thickness and diameter. Morphometric analysis of the diameter and g-ratio of the myelinated nerve fibers of the human sciatic nerve during the aging process.

Is the retinal nerve fiber free of myelin?

Histologically, myelin (and possibly oligodendrocytes) is present in the neural retinal nerve fiber layer, but the region of the lamina cribrosa is free of myelination.

Why is myelin important to the nervous system?

As part of the nervous system, myelin lines nerve fibers to protect and insulate neurons. Myelin aids in the quick and accurate transmission of electrical current carrying data from one nerve cell to the When myelin becomes damaged, the process involves numerous health conditions, including multiple sclerosis.