Is polycaprolactone water soluble?

PCL is soluble in chloroform, dichloromethane, carbon tetrachloride, benzene, toluene, cyclohexanone and 2-nitropropane at room temperature. It has a low solubility in acetone, 2-butanone, ethyl acetate, dimethylformamide and acetonitrile and is insoluble in alcohol, petroleum ether and diethyl ether [9].

What are solvent parameters?

Quantitative measures of the capability of solvents for interaction with solutes. Other solvent parameters are based on analysing experimental results. Such a parameter is considered to quantify some particular aspect of solvent capability for interaction with solutes.

At what temperature does polycaprolactone become pliable?

It has physical properties of a very tough, nylon-like plastic that softens to a putty-like consistency at only 60 °C, easily achieved by immersing in hot water. PCL’s specific heat and conductivity are low enough that it is not hard to handle by hand at this temperature.

How is poly ( ɛ-caprolactone ) solubility determined in a multiple emulsion?

During the process based on a multiple emulsion (W/O/W) with solvent evaporation/extraction method, the solvent has to dissolve a polymer, poly (ɛ-caprolactone) (PCL), which forms a polymeric matrix encapsulating or entrapping a therapeutic protein as the solvent is extracted.

Can you dissolve polycaprolactone in acetic acid media?

Join ResearchGate to ask questions, get input, and advance your work. you can dissolve it in any acidic media, even only acetic acid can dissolve it after 5-6 hour stirring at room temperature, if you increase the temperature it will reduce your stirring time.

How is the partial solubility of PCL determined?

Therefore the three partial solubility parameters of PCL have been determined by a group contribution method, swelling experiments and turbidimetric titration. The results obtained allowed us to find a solvent, anisole, able to solubilize PCL and to form a multiple emulsion with aqueous solutions.

Which is the least toxic solvent for PCL?

Solubility of polycaprolactone (PCL). Solubility of polycaprolactone (PCL). Can we dissolve PCL in mixture of acetic and formic acids? and which is the least toxic solvent for PCL? Join ResearchGate to ask questions, get input, and advance your work.