How does cisplatin work in chemotherapy?

How does cisplatin work in chemotherapy?

Cisplatin binds to the N7 reactive center on purine residues and as such can cause deoxyribonucleic acid (DNA) damage in cancer cells, blocking cell division and resulting in apoptotic cell death.

Do you lose your hair with cisplatin chemo?

v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment.

Does cisplatin cause chemo brain?

Chemotherapy-related cognitive deficits are a major neurological problem, but the underlying mechanisms are unclear. The death of neural stem/precursor cell (NSC) by cisplatin has been reported as a potential cause, but this requires high doses of chemotherapeutic agents.

How long does it take to recover from cisplatin?

Nadir: Meaning low point, is the point in time between chemotherapy cycles in which you experience low blood counts. Nadir: 18-23 days. Recovery: 39 days.

What is cisplatin used for?

Cisplatin is used to treat various types of cancer. It is a chemotherapy drug that contains platinum. It is used to slow or stop cancer cell growth.

What should I do to prepare for chemo?

The nutritional needs of people with cancer, including those who are preparing for chemotherapy or radiation, however, may require high-calorie, high-protein foods, such as milk, cream, cheese, and cooked eggs. Other recommendations may include cooking with more sauces, gravies, butter, margarine, or oil.

What should I expect with chemo?

What to Expect, from Someone Who’s Been There There are different types of chemotherapy. I have metastatic disease now, meaning cancer has spread to more than one place in my body. Always have a back-up plan when you have to go to the hospital for treatment. Sometimes the car won’t start. Not all chemo drugs cause hair loss. Feeling uneasy is normal. Always ask the “what if” questions.

What are the long term effects of chemotherapy?

Long-Term Side Effects of Chemotherapy Common long-term side effects of chemotherapy include early menopause and weight gain. Rare side effects include heart problems and leukemia.